Projects

Project I: Osteoclast precursors in inflamed tissues.

Host institution: ACTA, VU University Amsterdam, The Netherlands
Supervisors: Prof. Vincent Everts & Dr. Teun de Vries
Student: Sara Sprangers

Project II: Identification of molecular markers for a specific subset of osteoclasts in inflammation related bone pathologies.

Host Institution: ACTA, VU University Amsterdam, The Netherlands
Supervisors: Prof. Vincent Everts & Dr. Teun de Vries
Student: Yixuan Cao

Project III: Heterogeneity in osteoclast formation and proteolytic enzymes in retinoid treated mice.

Host Institution: Göteborgs Universitet, Sweden
Supervisors: Prof. Ulf Lerner & Dr. Petra Henning
Student: Vikte Lionikaite

Project IV: Cytoskeletal components and their role in sealing zone and ruffled border formation.

Host Institution: Technische Universitaet, Dresden, Germany
Supervisor: Prof. Bernard Hoflack
Student: Sandra Segeletz

Project V: Analysis of mouse models and osteoclast function with lysosomal deficiencies.

Host Institution: Christian-Albrechts Universitaet zu Kiel, Germany
Supervisors: Prof. Paul Saftig & Dr. Markus Damme
Student: David Massa Lopez

Project VI: Mechanisms/molecules essential in sealing zone and ruffled border formation, focus on autophagy and transcytosis.

Host Institution: University of Aberdeen, United Kingdom
Supervisors: Prof. Miep Helfrich & Dr. Fraser Coxon
Student: Anh Nhi Tran

Project VII: Studying vesicular content and trafficking in osteoclasts using advanced imaging and proteomic techniques.

Host Institution: University of Turku, Finland
Supervisor: Dr. Tiina Laitala-Leinonen
Student: Arjen Gebraad

Project VIII: Studying vesicular content and trafficking in osteoclasts using advanced imaging, including TEM tomography.

Host institution: University of Aberdeen, United Kingdom
Supervisors: Prof. Miep Helfrich & Dr. Fraser Coxon
Student: Emma McDermott

Project IX: Regulation of osteoclast subsets by systemic and local factors.

Host Institution: Karolinksa Institute, Stockholm, Sweden
Supervisor: Prof. Göran Andersson
Student: Laia Mira Pascual

Project X: Modulation of formation and activity of different subsets of osteoclasts by anti-resorptive compounds, focus on assay development.

Host Institution: Future Diagnostics, Wijchen, The Netherlands & Radboud University, Nijmegen, The Netherlands
Supervisors: Dr. Ernst Lindhout & Dr. Peter van Lent
Student: Giuliana Ascone

Project XI: Communication between osteoclasts and the extracellular matrix.

Host Institution: Nordic Bioscience, Herlev, Denmark
Supervisor: Dr. Kim Henriksen
Student: Henrik Löfvall